The MINT study

There is now scientific evidence that manual therapy can be effective for non-specific back and neck pain. However, the state of knowledge regarding how to best combine different manual medicine techniques is insufficient.

About the study

Purpose

The Manual Intervention Trial (MINT) is a comprehensive randomized controlled trial with three treatment arms that included 1,057 people who sought naprapathic care at the Scandinavian College of Naprapathic Manual Medicine's clinic for back and/or neck pain. The primary purpose of conducting MINT was to compare the effect of different combinations of naprapathic manual therapy (massage, muscle stretching, spinal manipulation, and spinal mobilization), both regarding desired effects such as pain relief and increased function, and regarding adverse treatment reactions immediately following manual treatment. Secondary purposes are to study the primary research questions in subgroups of patients and to study factors that are significant for the prognosis of back and/or neck pain.

The study, which was conducted in collaboration between the Scandinavian College of Naprapathic Manual Medicine and the Musculoskeletal & Sports Injury Epidemiology Center at Karolinska Institutet, began in 2010. The study participants answered questionnaires at the start of the study and on four occasions during the following year. The very extensive material in MINT has formed a significant part of two doctoral theses at Karolinska Institutet, supervised by the principal of the Scandinavian College of Naprapathic Manual Medicine, Eva Skillgate.

Staff at the Scandinavian College of Naprapathic Manual Medicine involved in MINT:

Eva Skillgate, licensed naprapath, associate professor and member of the Scandinavian College of Naprapathic Manual Medicine's scientific council (project manager)

Kari Paanalahti, licensed naprapath, lecturer, PhD

Martin Asker, licensed naprapath, lecturer, doctoral student

Jessica Lyander, licensed naprapath, lecturer

Publications based on MINT

  • Paanalahti KJ, Holm LW, Nordin M, Asker M, Lyander J, Skilllgate E. Adverse events after manual therapy among patients seeking care for neck and/or back pain. A randomized controlled trial. BMC Musculoskelet Disorders 2014 Mar 12;15:77. doi: 10.1186/1471-2474-15-77.
  • Palmlöf L, Holm LW, Alfredsson L, Skillgate E. Expectations of recovery – a prognostic factor in patients with neck pain undergoing manual therapy treatment. Submitted 2015 to European Journal of Pain.
  • Paanalahti Kari. Naprapathic manual therapy and other factors of importance for the prognosis of neck and back pain. Karolinska Institutet 2014. ISBN: 978-91-7549-640-5.
  • Palmlöf Lina. Neck pain – factors of importance for the prognosis. Karolinska Institutet 2014. ISBN: 978-91-7549-633-7.